"Game Over"s are the screens that cause you to lose the game.
Scared Your Love[]
When you confess to Makio Sono after murdering anyone other than your rivals, you will say to him, "I killed her for you!". This will scare him and induce a game over.
When you drag a body, murder, or are seen with a weapon by a corpse around Makio, he will say, "You Monster!" and cause a game over.
Caught by the Teacher[]
When a teacher witnesses Akari committing murder or dragging a corpse, they will attempt to apprehend her immediately.
The teacher will chokehold Akari, attempting to cause her to pass out. This will cause a game over.
This rule applies to justice-minded students as well.