"Game Over"s are the screens that cause you to lose the game.

Scared Your Love

When you confess to Makio Sono after murdering anyone other than your rivals, you will say to him, "I killed her for you!". This will scare him and induce a game over.

When you drag a body, murder, or are seen with a weapon by a corpse around Makio, he will say, "You Monster!" and cause a game over.

Caught by the Teacher

When a teacher witnesses Akari committing murder or dragging a corpse, they will attempt to apprehend her immediately.

The teacher will chokehold Akari, attempting to cause her to pass out. This will cause a game over.

This rule applies to justice-minded students as well.